Chromatin regulation and dynamics / edited by Anita Göndör.

Format
Book
Language
English
Published/​Created
Amsterdam : Elsevier Academic Press, [2017]
Description
xxii, 473 pages : illustrations ; 25 cm.

Availability

Copies in the Library

Location Call Number Status Location Service Notes
Lewis Library - Stacks QH599 .C458 2017 Browse related items Request

    Details

    Subject(s)
    Series
    Translational epigenetics series [More in this series]
    Summary note
    "Chromatin regulation and dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, and then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The book also covers the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin regulation and dynamics, as part of the Translational epigenetics series, facilitates the flow of information between research areas such as chromatin regulation, developmental biology, as well as ageing and complex diseases by focusing on recent findings of the fast-moving field of chromatin regulation."-- Provided by publisher.
    Bibliographic references
    Includes bibliographical references and index.
    Contents
    • A brief introduction to chromatin regulation and dynamics
    • Histone modifications and histone variants in pluripotency and differentiation
    • Dynamics and function of DNA methylation during development
    • ATP-dependent chromatin remodeling : from development to disease
    • Chromatin dynamics during the cell cycle
    • Epigenetic regulation of replication and replication timing
    • Regulation of cellular identity by polycomb and trithorax proteins
    • Interplay between chromatin and splicing
    • Crosstalk between non-coding RNAs and the epigenome in development
    • Epigenetic regulation of nucleolar functions
    • Chromatin dynamics and DNA repair
    • Regulation of centromeric chromatin
    • Telomere maintenance in the dynamic nuclear architecture
    • Epigenetic regulation of X-chromosome inactivation
    • Interaction between cellular metabolic states and chromatin dynamics
    • Circadian plasticity of chromatin states
    • 3D nuclear architecture and epigenetic memories : regulators of phenotypic plasticity in development, aging, and cancer.
    ISBN
    • 9780128033951 ((hardcover))
    • 0128033959 ((hardcover))
    LCCN
    2017288353
    OCLC
    938383599
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