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Mouse genetics and transgenics : a practical approach / edited by Ian J. Jackson and Catherine M. Abbott.
Format
Book
Language
English
Published/Created
Oxford ; New York : Oxford University Press, ©2000.
Description
xxiv, 299 p. ; 25 cm.
Availability
Copies in the Library
Location
Call Number
Status
Location Service
Notes
Lewis Library - Stacks
QH470.M52 M68 1999
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Details
Subject(s)
Mice
—
Genetics
—
Laboratory manuals
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Mice
—
Breeding
—
Laboratory manuals
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Transgenic mice
—
Laboratory manuals
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Mice as laboratory animals
—
Laboratory manuals
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Animal housing
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Transgenic mice
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Related name
Jackson, Ian J.
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Abbott, Catherine M.
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Library of Congress genre(s)
Laboratory manuals
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Series
Practical approach series ; 217.
[More in this series]
The practical approach series ; 217
Summary note
"Mouse Genetics and Transgenics: A Practical Approach is set to become a classic laboratory guide to the mouse. All major aspects are covered including: care and husbandry; archiving stocks as frozen embryos or sperm; mapping mutations and phenotypic trait loci; genetic and physical mapping of genomes; mouse cytogenetics and FISH; making new mutations by chemical mutagenesis or by directed mutagenesis through targeting in ES cells; making transgenic mice from plasmids, BACs and YACs; spatial analysis of gene expression. Details of the many databases for mouse researchers are also included together with specific guidance on information gathering and dissemination via the Internet."--BOOK JACKET. "This book will be an invaluable laboratory companion for every mouse researcher and for human geneticists who want to turn to the mouse model to address problems of human disease."--Jacket.
Bibliographic references
Includes bibliographical references.
Contents
Ch. 1. Mouse care and husbandry
Ch. 2. Cryopreservation and rederivation of embryos and gametes
Ch. 3. Spatial analysis of gene expression
Ch. 4. Mapping phenotypic trait loci
Ch. 5. Mapping genomes
Ch. 6. Mouse cytogenetics and FISH
Ch. 7. Electronic tools for accessing the mouse genome
Ch. 8. Mutagenesis of the mouse germline
Ch. 9. Generation of transgenic mice from plasmids, BACs and YACs
Ch. 10. Directed mutagenesis in embryonic stem cells.
Show 7 more Contents items
ISBN
0199637091 ((hbk.))
9780199637096 ((hbk.))
0199637083 ((pbk.))
9780199637089 ((pbk.))
LCCN
99037591
OCLC
41628278
Statement on language in description
Princeton University Library aims to describe library materials in a manner that is respectful to the individuals and communities who create, use, and are represented in the collections we manage.
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Mouse genetics and transgenics : a practical approach / edited by Ian J. Jackson and Catherine M. Abbott.
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SCSB-4788594