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Development of vaccines : from discovery to clinical testing / edited by Manmohan Singh, Indresh K. Srivasta.
Format
Book
Language
English
Published/Created
Hoboken, N.J. : John Wiley & Sons, ©2011.
Description
xiii, 454 pages : illustrations (some color) ; 25 cm
Availability
Available Online
Ebook Central Perpetual, DDA and Subscription Titles
Copies in the Library
Location
Call Number
Status
Location Service
Notes
Lewis Library - Stacks
QR189 .D48 2011
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Details
Subject(s)
Vaccines
[Browse]
Drug development
[Browse]
Drug stability
[Browse]
Related name
Manmohan Singh, 1964 November 8-
[Browse]
Srivasta, Indresh K.
[Browse]
Summary note
This book outlines the critical steps, and analytical tools and techniques, needed to take a vaccine from discovery through a successful clinical trial. Contributions from leading experts in the critical areas of vaccine expression, purification, formulation, pre-clinical testing and regulatory submissions make this book an authoritative collection of issues, challenges and solutions for progressing a biologic drug formulation from its early stage of discovery into its final clinical testing. A section with details and real-life experiences of toxicology testing and regulatory filing for vaccines is also included.
Bibliographic references
Includes bibliographical references and index.
Contents
Microbial vaccines design : the reverse vaccinology approach / Roberto Rosini, Michele A. Barocchi, Rino Rappuoli
Design and development of recombinant vaccines with viral properties / Gerd Lipowsky, Martin F. Bachmann
Tools for vaccine design : prediction and validation of highly immunogenic and conserved class II epitopes, and development of epitope-driven vaccines / Anne S. De Groot ... [et al.]
Virus like-particle vaccines advantages and challenges / Ted M. Ross ... [et al.]
Design platforms of nanocapsules for human therapeutics or vaccines / Masaaki Kawano ... [et al.]
Designing immunogens for vaccine development in reference to HIV / Aemro Kassa ... [et al.] --
Expression and purification of recombinant proteins for vaccine applications / Carlo Zambonelli, Deeann Martinez-Guzmann, and Indresh K. Srivastava
DNA vaccines for infectious diesase / Samuel Stepenson, Manmohan Singh, Indresh K. Srivastava
Developing stable cell lines for the production of vaccine antigens / Xiaotian Zhong ... [et al.]
Spectroscopy of vaccines / C. Russell Middaugh, Sangeeta B. Joshi
Biophysical characterization of protein antigens within vaccine formulations / Padima Malyala, Derek O'Hagan, Manmohan Singh
Structural characteristics predict the stability of HIV / Zohar Biron ... [et al.]
Selection of optimal adjuvants and product factors that affect vaccine immunogenicity / Wei Wang, Manmohan Singh
Lyophilization and stabilization of vaccines / James Chesko ... [et al.]
Effect of buffers and stabilizers on vaccine stability and efficacy / Shireesh P. Apte, Sydney Ugwu
Selection of final product containers / Luis Baez, Adrian Distler
From the lab to the clinic : filing a phase I IND for an investigational vaccine / Kenneth G. Surowitz.
Show 14 more Contents items
ISBN
9780470256374 ((cloth))
0470256370 ((cloth))
9781118023648 ((oBook))
1118023641 ((oBook))
9781118023624 ((ePDF))
1118023625 ((ePDF))
9781118023631 ((ePub))
1118023633 ((ePub))
LCCN
2010048282
OCLC
682072290
Statement on language in description
Princeton University Library aims to describe library materials in a manner that is respectful to the individuals and communities who create, use, and are represented in the collections we manage.
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Development of vaccines [electronic resource] : from discovery to clinical testing / edited by Manmohan Singh, Indresh K. Srivastava.
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99125355218506421